Advancements in Defining and Estimating the Reproduction Number in Infectious Disease Epidemiology
The reproduction number serves as a fundamental metric in the examination of infectious disease outbreaks, epidemics, and pandemics. …
Evaluation of the transmissibility of norovirus and the effectiveness of prevention and control measures for schools in Jiangsu Province
Objective This study aims to estimate the transmissibility of norovirus outbreaks in schools by different transmission routes, and to …
Epidemiological characteristics and transmissibility of HPV infection: A long-term retrospective study in Hokkien Golden Triangle, China, 2013-2021
Background Multiple human papillomavirus (HPV)-associated diseases have put a significant disease burden on the world. Therefore, we …
Assessment of transmissibility and measures effectiveness of SARS in 8 regions, China, 2002-2003
Background Severe acute respiratory syndrome (SARS) is a form of atypical pneumonia which took hundreds of lives when it swept the …
Trends in disease burden of hepatitis B infection in Jiangsu Province, China, 1990–2021
Background The incidence of hepatitis B virus (HBV) has decreased year by year in China after the expansion of vaccination, but there …
Impact of public health and social measures on contact dynamics during a SARS-CoV-2 Omicron variant outbreak in Quanzhou, China, March to April 2022
Objectives To evaluate the impact of early implementation of public health and social measures (PHSMs) on contact rates over time and …
Simulating potential outbreaks of Delta and Omicron variants based on contact-tracing data: A modelling study in Fujian Province, China
Although studies have compared the relative severity of Omicron and Delta variants by assessing the relative risks, there are still …
A follow up study of cycle threshold values of SARS-CoV-2 in Hunan Province, China
Since the epidemic of the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2), many governments have used reverse …
Contact pattern, current immune barrier, and pathogen virulence determines the optimal strategy of further vaccination
Background: The current outbreak of novel coronavirus disease 2019 has caused a serious disease burden worldwide. Vaccines are an …
Feasibility of emulating Singapore’s experience during the Omicron wave in China: a modelling study
The world has undergone five waves of COVID-19 pandemics, with a sixth wave likely to be led by China as policies in China begin to …
A comparative study on the three calculation methods for reproduction numbers of COVID-19
Objective: This study uses four COVID-19 outbreaks as examples to calculate and compare merits and demerits, as well as applicational …
Epidemiological Characteristics and Transmissibility of Human Immunodeficiency Virus in Nanning City, China, 2001-2020
Human immunodeficiency virus (HIV) is a single-stranded RNA virus that can weaken the body’s cellular and humoral immunity and is …
Viral dynamics of omicron BA.2.76 variant of SARS-CoV-2 in a cohort of COVID-19 patients
In order to reduce individual variations and estimate the positive duration (Ct value < 30), B-spline basis functions (using the …
Optimal control strategies of SARS-CoV-2 Omicron supported by invasive and dynamic models
Backqround: There is a raising concern of a higher infectious Omicron BA.2 variant and the latest BA.4, BA.5 variantmade it more …
Global differences in natural transmission rates of Monkeypox virus
The results showed the mean value of median Rt value for MPX of 1.36 (SD: 0.21) and the median R0 value of 1.63 (IQR: 1.34–1.72) where …
Epidemiology of tsutsugamushi disease and its relationship with meteorological factors in Xiamen city, China
Tsutsugamushi disease (TD) is an acute infectious disease caused by Orientia tsutsugamushi. This study aimed to analyze the …
Mathematical Models Supporting Control of COVID-19
Mathematical models have played an important role in the management of the coronavirus disease 2019 (COVID-19) pandemic. The aim of …
Study on the interaction between different pathogens of Hand, foot and mouth disease in five regions of China
Objectives This study aims to explore the interaction of different pathogens in Hand, foot and mouth disease (HFMD) by using a …
Natural history and cycle threshold values analysis of COVID-19 in Xiamen City, China
This study elaborated the natural history parameters of Delta variant, explored the differences in detection cycle thresholds (Ct) …
Comparative analysis of transmission and vaccine effectiveness in Omicron and Delta variant outbreaks in China
Our findings imply that Omicron’s transmissibility is 1.5–1.8 times higher than that of Delta in terms of viral transmission. …
Epidemiological characteristics of severe fever with thrombocytopenia syndrome and its relationship with meteorological factors in Liaoning Province, China
The annual incidence of SFTS increased year on year in Liaoning Province. Incidence of SFTS was affected by several meteorological …
儿童和青少年新型冠状病毒感染的研究进展
随着成年人大规模接种新型冠状病毒（新冠病毒）疫苗，儿童和青少年群体由于较低疫苗覆盖率和较高接触度，逐渐成为新冠病毒感染的脆弱人群，有必要总结儿童和青少年群体新冠病毒感染特征、新冠病毒疫苗对于变异株的免疫效果。本文检索现有文献，对儿童和青少年新冠病毒感染的研究进展进行综 …
Computing R0 of dynamic models by a definition-based method
Objectives: Computing the basic reproduction number (R 0) in deterministic dynamical models is a hot topic and is frequently demanded …
Meteorological factors and tick density affect the dynamics of SFTS in jiangsu province, China
This study aimed to explore whether the transmission routes of severe fever with thrombocytopenia syndrome (SFTS) will be affected by …
Correlation between mumps and meteorological factors in Xiamen City, China: A modelling study
Objective Mumps is a seasonal infectious disease, always occurring in winter and spring. In this study, we aim to analyze its …
Analysis of HFMD transmissibility among the whole population and age groups in a large city of China
Background: Hand-Foot-and-Mouth-Disease (HFMD) has been widely spread in Asia, and has result in a high disease burden for children in …
The optimal vaccination strategy to control COVID-19: a modeling study in Wuhan City, China
Background Reaching optimal vaccination rates is an essential public health strategy to control the coronavirus disease 2019 (COVID-19) …
The transmission dynamics of Middle East Respiratory Syndrome coronavirus
Background: In this study, we aimed to quantify the contribution of different transmission routes of the MiddleEast respiratory …
Feasibility of Booster Vaccination in High-Risk Populations for Controlling Coronavirus Variants - China, 2021
Introduction: Vaccination booster shots are completely necessary for controlling breakthrough infections of severe acute respiratory …
Modelling the transmission dynamics of severe fever with thrombocytopenia syndrome in Jiangsu Province, China
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease that is regionally distributed in Asia, with high …
Live poultry feeding and trading network and the transmission of avian influenza A(H5N6) virus in a large city in China, 2014-2015
Objectives:To understand the transmission mechanisms of the avian influenza A(H5N6) virus. Methods:This study explored the live poultry …
Epidemiological Characteristics and Transmissibility for SARS-CoV-2 of Population Level and Cluster Level in a Chinese City
Background: To date, there is a lack of sufficient evidence on the type of clusters in which severe acute respiratory syndrome …
A five-compartment model of age-specific transmissibility of SARS-CoV-2
Background The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, also called 2019-nCoV) causes different …
Comparative analysis of transmission and vaccine effectiveness in Omicron and Delta variant outbreaks in China
Background Developing countries exhibit a high disease burden from shigellosis. Owing to the different incidences in males and females, …
Transmission pattern of shigellosis in Wuhan City, China: a modelling study
The article aims to estimate and forecast the transmissibility of shigellosis and explore the association of meteorological factors …
Transmissibility of tuberculosis among students and non-students: an occupational-specific mathematical modelling
Background: Recently, despite the steady decline in the tuberculosis (TB) epidemic globally, school TB outbreaks have been frequently …
Shigellosis seasonality and transmission characteristics in different areas of China: A modelling study
Objective In China, the burden of shigellosis is unevenly distributed, notably across various ages and geographical areas. Shigellosis …
Relative transmissibility of shigellosis among different age groups: A modeling study in Hubei Province, China
Shigellosis is a heavy disease burden in China especially in children aged under 5 years. However, the age-related factors involved in …
Hepatitis E in 24 Chinese Cities, 2008-2018: A New Analysis Method for the Disease's Occupational Characteristics
Background: The disease burden of hepatitis E remains high. We used a new method (richness, diversity, evenness, and similarity …
Feasibility of Hepatitis C Elimination in China: From Epidemiology, Natural History, and Intervention Perspectives
Hepatitis C imposes a heavy burden on many countries, including China, where the number of reported cases and the incidence of …
Feasibility of containing shigellosis in Hubei Province, China: a modelling study
Background: The transmission features and the feasibility of containing shigellosis remain unclear among apopulation-based study in …
Early warning of hand, foot, and mouth disease transmission: A modeling study in mainland, China
Background Hand, foot, and mouth disease (HFMD) is a globalinfectious disease; particularly, it has ahigh disease burden in China. This …
