2025

Evaluation and optimization of mumps-containing vaccination strategies: a study based on an individual-based stochastic model

**Background** The measles-mumps-rubella (MMR) trivalent vaccine constitutes a cornerstone in controlling mumps incidence. However, variations in vaccination timing coupled with the gradual waning of vaccine-induced immunity have contributed to an …

Phage therapy against Klebsiella pneumoniae: An evolving perspective

Klebsiella pneumoniae represents one of the most concerning ESKAPE pathogens, with multidrug-resistant strains driving urgent clinical interest in phage therapy as a viable alternative to antibiotics. However, the evolutionary arms race between …

Estimating the transmissibility of the 2025 chikungunya fever outbreak in Foshan, China: a modelling study

**Background** Following the onset of an index chikungunya case on July 8, 2025, a significant outbreak occurred in Foshan, Guangdong Province, China. This study aimed to quantify the outbreak's transmissibility between June 16 and July 21, 2025. …

Feasibility of ending tuberculosis in Shangrao City through active intervention measures: a mathematical study

**Objective** China faces significant challenges in ending tuberculosis (TB). Active case finding (ACF) and TB preventive therapy (TPT) have proven to be critical measures in reducing TB incidence. This study uses a transmission dynamics model to …

Multi-modal Adaptive Estimation for Temporal Respiratory Disease Outbreak

**Background** Despite the high coverage of childhood vaccination, pertussis remains a significant global health challenge, with increasing adult cases attributed to waning immunity and enhanced diagnostic capability. This study quantified the global …

Forecasting high-risk areas for dengue outbreaks in China: A trend analysis of Aedes albopictus and Aedes aegypti distributions from 2014 to 2030

**Background** Global warming, urbanization and the resumption of global population movements post-COVID-19 have made the prevention and control of dengue and its vector transmission more challenging. To tackle this issue, this study evaluated and …

Characteristics and risk factors for outcomes in patients with Mycoplasma pneumoniae mono- and coinfections: A ulticenter surveillance study in Wuhan, China, 2023

**Objectives** Mycoplasma pneumoniae (MP) is a key cause of community-acquired pneumonia, and coinfections lead to varied patient outcomes. A comprehensive understanding of the outcome characteristics and associated etiologies of coinfections in MP …

Detection and prevalence of avian influenza epidemic in the southwest of Poyang Lake and analysis of the influence of meteorological factors

Recently, the epidemiological profile of avian influenza has changed dramatically worldwide. Avian influenza sampling and surveillance of wholesale and retail markets in Nanchang, the largest city in the southwestern region of Poyang Lake, have been …

Spatial and temporal distribution patterns and factors influencing hepatitis B in China: a geo-epidemiological study

Recently, the epidemiological profile of avian influenza has changed dramatically worldwide. Avian influenza sampling and surveillance of wholesale and retail markets in Nanchang, the largest city in the southwestern region of Poyang Lake, have been …